Overview

SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.7
USERS' SCORE
Good
Based on 11 Reviews
8.1
Supplement Facts
Serving Size:  1 Softgel
Amount Per Serving
%DV
Calories
15
 
Total Fat
1.5 g
2%‡
Evening Primrose Seed Oil (Oenothera biennis)
1,300 mg
GLA (Gamma-Linolenic Acid)
130 mg

Top Medical Research Studies

8
Evening primrose oil shows promise
We analyzed how different types of dietary fats might influence breast cancer growth. In our study, we used athymic mice with human breast cancer cells and supplemented their diets with evening primrose oil and fish oil, while others received olive oil or a standard diet without essential fatty acids.

We found that the tumors in the mice receiving evening primrose oil were significantly smaller compared to those on a standard diet — suggesting that increasing essential fatty acids could play a beneficial role in managing breast cancer.
Read More
7
Evening primrose oil enhances tamoxifen
We explored the potential of evening primrose oil (EPO) to enhance the effects of tamoxifen—an established breast cancer treatment. In laboratory tests using human breast cancer cell lines, EPO showed promising results, working alongside tamoxifen to encourage cancer cell death and stop cell growth.

While our findings suggest that EPO can improve tamoxifen's anticancer abilities, more research is needed to fully understand its impact on breast cancer treatment in patients.
Read More
5
Evening primrose oil shows limited effects
We conducted a randomized, double-blind, controlled trial to explore the effects of fish oil and evening primrose oil (EPO) on breast cancer patients undergoing chemotherapy. Over 12 weeks, participants received either the oil supplements or a placebo.

While we noted improvements in fatty acid profiles in the treatment group, the study showed no significant changes in inflammatory markers between the two groups. Despite a decrease in IL-6 levels in the intervention group, there was no major benefit observed overall.

Ultimately, our findings suggest that while this supplementation can help with lipid metabolism, it does not deliver significant anti-inflammatory effects for breast cancer patients undergoing chemotherapy.
Read More

Most Useful Reviews

9
Eliminates PMS symptoms
34 people found this helpful
I tried this superhero butter out of curiosity, and it completely eradicated my PMS symptoms for months! Previously, I experienced breast soreness for 10 days prior to my period, but now I hardly notice any symptoms. I forget about my monthly cycle entirely—no pain or discomfort at all! I might take it a few times a year. Thanks, iHerb! I’ll definitely remember it for when I eventually give birth!
Read More
7.5
Menopause support
1 people found this helpful
I find great support from evening primrose oil for my menopause and breast health. Coupling it with progesterone cream works wonders for me and helps balance my hormonal levels effectively.
Read More
6
Decreases PMS symptoms
1 people found this helpful
I take this oil for women's health for myself and my mother to balance female hormones. In the second phase of my cycle, I've noticed a reduction in PMS symptoms, less irritability, decreased breast swelling, and less painful menstruation.
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.7
  • All Researches
8
Evening primrose oil shows promise
We analyzed how different types of dietary fats might influence breast cancer growth. In our study, we used athymic mice with human breast cancer cells and supplemented their diets with evening primrose oil and fish oil, while others received olive oil or a standard diet without essential fatty acids.

We found that the tumors in the mice receiving evening primrose oil were significantly smaller compared to those on a standard diet — suggesting that increasing essential fatty acids could play a beneficial role in managing breast cancer.
Read More
7
Evening primrose oil enhances tamoxifen
We explored the potential of evening primrose oil (EPO) to enhance the effects of tamoxifen—an established breast cancer treatment. In laboratory tests using human breast cancer cell lines, EPO showed promising results, working alongside tamoxifen to encourage cancer cell death and stop cell growth.

While our findings suggest that EPO can improve tamoxifen's anticancer abilities, more research is needed to fully understand its impact on breast cancer treatment in patients.
Read More
5
Evening primrose oil shows limited effects
We conducted a randomized, double-blind, controlled trial to explore the effects of fish oil and evening primrose oil (EPO) on breast cancer patients undergoing chemotherapy. Over 12 weeks, participants received either the oil supplements or a placebo.

While we noted improvements in fatty acid profiles in the treatment group, the study showed no significant changes in inflammatory markers between the two groups. Despite a decrease in IL-6 levels in the intervention group, there was no major benefit observed overall.

Ultimately, our findings suggest that while this supplementation can help with lipid metabolism, it does not deliver significant anti-inflammatory effects for breast cancer patients undergoing chemotherapy.
Read More

User Reviews

USERS' SCORE
Good
Based on 11 Reviews
8.1
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Eliminates PMS symptoms
34 people found this helpful
I tried this superhero butter out of curiosity, and it completely eradicated my PMS symptoms for months! Previously, I experienced breast soreness for 10 days prior to my period, but now I hardly notice any symptoms. I forget about my monthly cycle entirely—no pain or discomfort at all! I might take it a few times a year. Thanks, iHerb! I’ll definitely remember it for when I eventually give birth!
Read More
7.5
Menopause support
1 people found this helpful
I find great support from evening primrose oil for my menopause and breast health. Coupling it with progesterone cream works wonders for me and helps balance my hormonal levels effectively.
Read More
6
Decreases PMS symptoms
1 people found this helpful
I take this oil for women's health for myself and my mother to balance female hormones. In the second phase of my cycle, I've noticed a reduction in PMS symptoms, less irritability, decreased breast swelling, and less painful menstruation.
Read More
9
Relieves cyclical pain
Evening primrose oil is my preferred supplement for cyclical breast pain. After a few months, the pain almost completely diminishes.
Read More
9
Eases menopausal pain
My breast pain arose from changes in menopausal hormones. After taking this, the breast pain vanished.
Read More

Frequently Asked Questions

9
Relieves cyclical pain
Evening primrose oil is my preferred supplement for cyclical breast pain. After a few months, the pain almost completely diminishes.
7.5
Alleviates swelling
I take this due to hormonal imbalance, and it's effective for reducing breast swelling and pain.
9
Eases menopausal pain
My breast pain arose from changes in menopausal hormones. After taking this, the breast pain vanished.
9
Eliminates PMS symptoms
34 people found this helpful
I tried this superhero butter out of curiosity, and it completely eradicated my PMS symptoms for months! Previously, I experienced breast soreness for 10 days prior to my period, but now I hardly notice any symptoms. I forget about my monthly cycle entirely—no pain or discomfort at all! I might take it a few times a year. Thanks, iHerb! I’ll definitely remember it for when I eventually give birth!
6
Decreases PMS symptoms
1 people found this helpful
I take this oil for women's health for myself and my mother to balance female hormones. In the second phase of my cycle, I've noticed a reduction in PMS symptoms, less irritability, decreased breast swelling, and less painful menstruation.
7.5
Menopause support
1 people found this helpful
I find great support from evening primrose oil for my menopause and breast health. Coupling it with progesterone cream works wonders for me and helps balance my hormonal levels effectively.
7.5
Painless menstruation
Ideal for progesterone recovery, I consume one capsule in the second phase of the cycle. My menstruation has become painless and without breast swelling.
6
Improves breast pain
I have a large size, consuming two tablets weekly improves my breast pain.
7
Evening primrose oil enhances tamoxifen
We explored the potential of evening primrose oil (EPO) to enhance the effects of tamoxifen—an established breast cancer treatment. In laboratory tests using human breast cancer cell lines, EPO showed promising results, working alongside tamoxifen to encourage cancer cell death and stop cell growth.

While our findings suggest that EPO can improve tamoxifen's anticancer abilities, more research is needed to fully understand its impact on breast cancer treatment in patients.
8
Evening primrose oil shows promise
We analyzed how different types of dietary fats might influence breast cancer growth. In our study, we used athymic mice with human breast cancer cells and supplemented their diets with evening primrose oil and fish oil, while others received olive oil or a standard diet without essential fatty acids.

We found that the tumors in the mice receiving evening primrose oil were significantly smaller compared to those on a standard diet — suggesting that increasing essential fatty acids could play a beneficial role in managing breast cancer.
5
Evening primrose oil shows limited effects
We conducted a randomized, double-blind, controlled trial to explore the effects of fish oil and evening primrose oil (EPO) on breast cancer patients undergoing chemotherapy. Over 12 weeks, participants received either the oil supplements or a placebo.

While we noted improvements in fatty acid profiles in the treatment group, the study showed no significant changes in inflammatory markers between the two groups. Despite a decrease in IL-6 levels in the intervention group, there was no major benefit observed overall.

Ultimately, our findings suggest that while this supplementation can help with lipid metabolism, it does not deliver significant anti-inflammatory effects for breast cancer patients undergoing chemotherapy.

References

  1. Arsic A, Krstic P, Paunovic M, Nedovic J, Jakovljevic V, et al. Anti-inflammatory effect of combining fish oil and evening primrose oil supplementation on breast cancer patients undergoing chemotherapy: a randomized placebo-controlled trial. Sci Rep. 2023;13:6449. 10.1038/s41598-023-28411-8
  2. Abd-Alhaseeb MM, Massoud SM, Elsayed F, Omran GA, Salahuddin A. Evening Primrose Oil Enhances Tamoxifen's Anticancer Activity against Breast Cancer Cells by Inducing Apoptosis, Inhibiting Angiogenesis, and Arresting the Cell Cycle. Molecules. 2022;27. 10.3390/molecules27082391
  3. Pritchard GA, Jones DL, Mansel RE. Lipids in breast carcinogenesis. Br J Surg. 1989;76:1069.
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